Urinary Bladder Neoplasm

by | Oct 27, 2021 | Abdomen, Special Cases | 0 comments

Transitional cell carcinoma (TCC), also called urothelial cell carcinoma (UCC) of the bladder, is the most common primary neoplasm of the urinary bladder, and bladder TCC is the most common tumour of the entire urinary system.

Age: 52

Sex : Male

CASE DISCUSSION

The bladder is by far the most common site of transitional cell carcinomas, 50 times more common than TCC of the renal pelvis, and 100 times more common than TCC of the ureter 1. Bladder TCCs are the most common tumour of the entire urinary tract.

There is a known association of TCCs developing within bladder diverticula, presumably due to urinary stasis which leads to chronic urothelial irritation and potentially exaggerated exposure to urinary carcinogens 10-12.

REFERENCE

  1. Explore expert insights into key ASCO21 data plus complimentary access to 50 official presentations and downloadable slides
    ASCO Direct 2021
  2. Surgically treated transitional cell carcinomas of the bladder. The role of radical surgery
    Muneer A. Al-Ali et al., Saudi Medical Journal, 2002
  3. Intravesical immunotherapy for superficial bladder cancer
    Mohammad T. Said et al., Saudi Medical Journal, 2002
  1. Overexpression of normal and mutated forms of HRAS induces orthotopic bladder invasion in a human transitional cell carcinoma.
    D Theodorescu et al., Proc Natl Acad Sci U S A, 1990
  2. Bladder Cancer: A Review
    Andrew T. Lenis et al., Journal of American Medical Association, 2020
  3. Non-muscle-invasive clear cell carcinoma of the urinary bladder: Is cystectomy necessary?
    Tamani Jayawardhana et al., Case Rep, 2019